Low-protein corn-starch based diets exclude role of toxic factors from tapioca in induction of mucoid vasculopathy and associated disorders
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Date
1996
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Journal Title
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Volume Title
Publisher
TROPICAL TUBER CROPS: PROBLEMS, PROSPECTS AND FUTURE STRATEGIES
Abstract
Using low-protein tapioca-starch-based diets, degenerative cardiovascular changes similar to those in the human disorder, mucoid vasculopathy, were induced in a monkey model. The experiments were repeated using low-protein corn-starch-substituted diets and identical changes were obtained. The experiments demonstrated the etiologic role of protein deficiency in mucoid vasculopathy and lesion enhancement by either tapioca-starch or corn-starch in protein-deficient state. The experiments excluded the possibility of any toxic factors from tapioca starch in inducing the changes. The role of high carbohydrate (irrespective of the source) with low-protein intake in the development of degenerative diseases could also be established.
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Keywords
Agriculture; Biotechnology & Applied Microbiology; Food Science & Technology
Citation
,;467-470