Adsorption of human IgG on Cu2+-immobilized cellulose affinity membrane: Preliminary study

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dc.contributorHari, PR
dc.contributorPaul, W
dc.contributorSharma, CP
dc.date.accessioned2012-12-04T11:43:18Z
dc.date.available2012-12-04T11:43:18Z
dc.date.issued2000
dc.description.abstractImmobilized metal ion affinity chromatography (IMAC) is widely used. Transition metal ions have a high affinity to some peptide sequences. We have studied the selective adsorption of human IgG from a mixture of albumin, gamma-globulin, fibrinogen, and IgG onto Cu2+ ion-immobilized cellulose membrane. Although Cu2+ ligand is selective to IgG, in general gamma-globulins also are adsorbed. The simplicity and lower cost of Cu2+ ion-immobilized cellulose membranes may be useful for removing IgG from blood. (C) 2000 John Wiley & Sons, Inc.
dc.identifier.citationJOURNAL OF BIOMEDICAL MATERIALS RESEARCH. 50; 2; 110-113en_US
dc.identifier.urihttp://dx.doi.org/10.1002/(SICI)1097-4636(200005)50:2<110
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/73
dc.publisherJOURNAL OF BIOMEDICAL MATERIALS RESEARCH
dc.subjectBiocompatibility
dc.titleAdsorption of human IgG on Cu2+-immobilized cellulose affinity membrane: Preliminary study
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