The significance of corpora amylacea in mesial temporal lobe epilepsy

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dc.contributorCherian, PJ
dc.contributorRadhakrishnan, VV
dc.contributorRadhakrishnan, K
dc.date.accessioned2012-12-04T11:45:33Z
dc.date.available2012-12-04T11:45:33Z
dc.date.issued2003
dc.description.abstractTemporal lobe epilepsy (TLE) associated with mesial temporal sclerosis (MTS), mesial TLE (MTLE), is the commonest medically refractory adult epilepsy syndrome. Corpora amylacea (CoA) have been shown to be a marker of MTS. We compared 9 patients with MTS who had dense deposition of CoA in their hippocampi with 25 patients with MTS who did not have CoA. The patients with CoA were significantly older and they showed a trend towards having a significantly longer duration of epilepsy. The postoperative seizure outcome at 2 years was not different in the 2 groups. Our results could indicate the progressive nature of the pathology of MTS, probably indicating excitotoxic damage due to recurrent seizures, but they need to be verified by clinicopathological correlation among a larger number of patients with MTLE.
dc.identifier.citationNEUROLOGY INDIA. 51; 2; 277-279en_US
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/14571029
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/1207
dc.publisherNEUROLOGY INDIA
dc.subjectNeurology
dc.titleThe significance of corpora amylacea in mesial temporal lobe epilepsy
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