Significance of circulating immune complexes in myasthenia gravis

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dc.contributorMathai, A
dc.contributorSarada, C
dc.contributorRadhakrishnan, VV
dc.date.accessioned2012-12-04T11:45:13Z
dc.date.available2012-12-04T11:45:13Z
dc.date.issued2000
dc.description.abstractIn this study, circulating immune complexes (CICs) were isolated and characterized in the sera of myasthenia gravis (MG) patients with thymoma and MG patients without any thymic lesions. High titres of antistriational antibodies in the CICs were demonstrated by an indirect immunofluorescence (IF) method in 60 per cent (15/25) MG patients with thymoma. The CICs showed a steady decrease in these 15 patients during the post thymectomy period. Antistriational antibodies in the CICs of MG patients without thymic lesions were not detected by IF method. The results of this study emphasised the usefulness of estimation of CICs in the overall management of MG patients with thymoma.
dc.identifier.citationINDIAN JOURNAL OF MEDICAL RESEARCH. 111; ; 180-183en_US
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/10943071
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/1046
dc.publisherINDIAN JOURNAL OF MEDICAL RESEARCH
dc.subjectNeurology
dc.titleSignificance of circulating immune complexes in myasthenia gravis
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