Glutamate microinjection at the medial preoptic area enhances slow wave sleep in rats
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Date
2011
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Journal Title
Journal ISSN
Volume Title
Publisher
BEHAVIOURAL BRAIN RESEARCH
Abstract
A large body of evidence has established the role of the medial preoptic area (mPOA) in regulation of slow wave sleep (SWS). Although the mPOA neurons contain excitatory neurotransmitter glutamate, its role in sleep-wakefulness is not known. In the present study microinjection of monosodium glutamate (40, 80 and 120 ng) into the mPOA augmented SWS. Earlier reports have shown enhancement of paradoxical sleep by glutamate in other brain areas. (C) 2010 Elsevier B.V. All rights reserved.
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Keywords
Behavioral Sciences; Neurosciences & Neurology
Citation
217 ,1;240-243