Delivery of insulin from hydroxyapatite ceramic microspheres: Preliminary in vivo studies

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dc.contributorPaul, W
dc.contributorNesamony, J
dc.contributorSharma, CP
dc.date.accessioned2012-12-04T11:43:47Z
dc.date.available2012-12-04T11:43:47Z
dc.date.issued2002
dc.description.abstractThe major limiting factor in utilizing protein drugs for sustained delivery is the lack of suitable delivery systems. Ceramic hydroxyapatite microspheres are biocompatible and utilized for the purification of proteins. As a preliminary study, we have investigated the possibility of using hydorxyapatite ceramic microspheres loaded with insulin as an implantable delivery system in rats. With this limited test, it was shown-that the loaded insulin was active and able to suppress the blood glucose level in normal rats. (C) 2002 Wiley Periodicals, Inc.
dc.identifier.citationJOURNAL OF BIOMEDICAL MATERIALS RESEARCH. 61; 4; 660-662en_US
dc.identifier.urihttp://dx.doi.org/10.1002/jbm.10213
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/327
dc.publisherJOURNAL OF BIOMEDICAL MATERIALS RESEARCH
dc.subjectDrug Delivery
dc.titleDelivery of insulin from hydroxyapatite ceramic microspheres: Preliminary in vivo studies
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