Problem of bacterial contamination in platelet concentrates
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Date
2009
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
TRANSFUSION AND APHERESIS SCIENCE
Abstract
Bacterial contamination of blood is being recognized more frequently now and is one of the serious complications of transfusion. Use of integrally attached collection systems and strict standards for skin preparation, collection and storage of blood and components have reduced but not eliminated the risk of bacterial contamination. As bacteraemia may be part of acute or sub acute infections, strict donor selection is warranted. The longer the storage time, the greater is the number of organisms and amount of endotoxin present in the unit and associated with transfusion reactions. Importance of haemovigilance system and awareness among clinicians on the potential complications will go a long way in reducing patient morbidity. New approaches for detection of bacterial contamination, pathogen reduction and developments in the field of platelet biology will increase blood safety. (C) 2009 Elsevier Ltd. All rights reserved.
Description
Keywords
Hematology
Citation
TRANSFUSION AND APHERESIS SCIENCE. 41; 2; 139-144