Tissue engineered vascular graftspreclinical aspects

dc.contributor.author	Thomas, LV
dc.contributor.author	Lekshmi, V
dc.contributor.author	Nair, PD
dc.date.accessioned	2012-12-05T05:10:55Z
dc.date.available	2012-12-05T05:10:55Z
dc.date.issued	2012-10
dc.description.abstract	Tissue engineering enables the development of fully biological vascular substitutes that restore, maintain and improve tissue function in a manner identical to natural host tissue. However the development of the appropriate preclinical evaluation techniques for the generation of fully functional tissue-engineered vascular graft (TEVG) is required to establish their safety for use in clinical trials and to test clinical effectiveness. This review gives an insight on the various preclinical studies performed in the area of tissue engineered vascular grafts highlighting the different strategies used with respect to cells and scaffolds, typical animal models used and the major in vivo evaluation studies that have been carried out. The review emphasizes the combined effort of engineers, biologists and clinicians which can take this clinical research to new heights of regenerative therapy.
dc.identifier.citation	Int. J Cardiol. 2012	en_US
dc.identifier.uri	http://dx.doi.org/10.1016/j.ijcard.2012.09.069
dc.identifier.uri	https://dspace.sctimst.ac.in/handle/123456789/1292
dc.publisher	Int. J Cardiol.	en_US
dc.title	Tissue engineered vascular graftspreclinical aspects	en_US
dc.type	Article	en_US

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