Investigation of apoptotic events at molecular level induced by SERS guided targeted theranostic nanoprobe
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Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
NANOSCALE
Abstract
Herein, we have examined distinctive structural and functional variations of cellular components during apoptotic cell death induced by a targeted theranostic nanoprobe, MMP-SQ@GNR@LAH-DOX, which acted as a SERS "on/off" probe in the presence of a MMP protease and executed synergistic photothermal chemotherapy, as reflected by the SERS fingerprinting, corresponding to the phosphodiester backbone of DNA.
Description
Keywords
Chemistry; Science & Technology - Other Topics; Materials Science; Physics
Citation
8 ,22;11392-11397