Photopolymerized poly(2-hydroxyethyl methacrylate)/poly(epsilon-caprolactone)/poly(ethylene glycol) system as a potential wound dressing material
dc.contributor.author | Rethikala, PK | |
dc.contributor.author | Kalliyana, KV | |
dc.date.accessioned | 2017-03-10T03:28:03Z | |
dc.date.available | 2017-03-10T03:28:03Z | |
dc.date.issued | 2015 | |
dc.description.abstract | Polymeric hydrogel systems based on poly(2-hydroxyethyl methacrylate), poly(epsilon-caprolactone), and poly(ethylene glycol) were prepared by photopolymerization using 2,4,6-trimethyl benzoyl diphenyl phosphine oxide as the photoinitiator. The structural details, morphology, and crystallinity were evaluated by Fourier transform infrared, scanning electron microscope, and X-ray diffraction analysis. The fluid uptake of the hydrogels was measured using swelling analysis. Based on a hemolysis assay, the prepared hydrogels were non-hemolytic. No attachment of fibroblasts to the hydrogel systems was observed. Stress-strain results indicated that the poly(2-hydroxyethyl methacrylate), poly(epsilon-caprolactone), and poly(ethylene glycol) hydrogel system (85:10:5) possessed better mechanical properties. Cytotoxic assessment by direct contact method of 85:10:5 systems found that the hydrogel was non-cytotoxic to L929 fibroblasts. This hydrophilic polymer system has a potential for wound dressing applications. | |
dc.identifier.citation | 30 ,1;74-86 | en_US |
dc.identifier.uri | 10.1177/0883911514558543 | |
dc.identifier.uri | https://dspace.sctimst.ac.in/handle/123456789/10230 | |
dc.publisher | JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS | |
dc.subject | Biotechnology & Applied Microbiology; Materials Science; Polymer Science | |
dc.title | Photopolymerized poly(2-hydroxyethyl methacrylate)/poly(epsilon-caprolactone)/poly(ethylene glycol) system as a potential wound dressing material |