Spinal fixation device: A 6-year postimplantation study

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dc.contributorMohanty, M
dc.contributorBaby, S
dc.contributorMenon, KV
dc.date.accessioned2012-12-04T11:45:16Z
dc.date.available2012-12-04T11:45:16Z
dc.date.issued2003
dc.description.abstractLong-term tissue response to a metal device is described here. The components of a spinal fixation device were removed 6 years after implantation, following the need for revision surgery after a fall. Scanning electron microscopy (SEM) revealed changes in surface topography of the metal. Examination of the adjacent tissue showed a chronic inflammatory response with occasional metal debris. Immunohistochemistry identified the predominant macrophages and abundant neovascularization. The presence of macrophages in tissues adjacent to the implants, in an otherwise asymptomatic person, is noteworthy.
dc.identifier.citationJOURNAL OF BIOMATERIALS APPLICATIONS. 18; 2; 109-121en_US
dc.identifier.urihttp://dx.doi.org/10.1177/088532803034746
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/14621337
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/1068
dc.publisherJOURNAL OF BIOMATERIALS APPLICATIONS
dc.subjectMedical Devices
dc.titleSpinal fixation device: A 6-year postimplantation study
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