Electrodiagnostic and clinical aspects of Guillain-Barre syndrome: an analysis of 142 cases.

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dc.contributorGupta, Deepak
dc.contributorNair, Muraleedharan
dc.contributorBaheti, Neeraj N
dc.contributorSarma, PS
dc.contributorKuruvilla, Abraham
dc.date.accessioned2012-12-04T11:44:00Z
dc.date.available2012-12-04T11:44:00Z
dc.date.issued2008
dc.description.abstractBACKGROUND: The incidence of Guillain-Barre syndrome (GBS) and its subtypes varies throughout the world.OBJECTIVE AND METHODS: We present a retrospective analysis of 142 GBS cases, treated at our center, aimed at classifying GBS electrophysiologically, to study the sequential electrophysiological changes in cases with acute inflammatory demyelinating polyradiculoneuropathy (AIDP), and to look for any clinical and cerebrospinal fluid parameters that can also help in distinguishing the subtypes.RESULTS: One hundred twenty-one (85.2%) cases had AIDP, 15 (10.6%) had acute motor axonal neuropathy, and 6 (4.2%) were unclassifiable.CONCLUSIONS: Motor conduction blocks and temporal dispersion could be observed from days 3 and 5 onward, respectively. Progression of motor conduction slowing in AIDP was most impressive in the median nerves. Varying affection of deep tendon reflexes, cranial nerves, and cerebrospinal fluid albuminocytological dissociation can also help make a distinction between AIDP and acute motor axonal neuropathy. Sural sparing, a marker of demyelinating neuropathy, is more commonly seen in later than in early stages of AIDP.
dc.identifier.citationJournal of clinical neuromuscular disease. 10; 2; 42-51en_US
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/437
dc.publisherJournal of clinical neuromuscular disease
dc.subjectNeurology
dc.titleElectrodiagnostic and clinical aspects of Guillain-Barre syndrome: an analysis of 142 cases.
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