Seven-year longitudinal change in risk factors for non-communicable diseases in rural Kerala, India: The WHO STEPS approach.
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Date
2017-06
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Plos one
Abstract
Nearly three-quarters of global deaths from non-communicable diseases (NCDs) occur in
low- and middle-income countries such as India. However, there are few data available on
longitudinal change in risk factors for NCDs in India. We conducted a cohort study among
495 individuals (aged 15 to 64 years at baseline) in rural Kerala state, India, from 2003 to
2010. For the present analysis, data from 410 adults (aged 20 to 64 years at baseline) who
participated at both baseline and follow-up studies were analyzed. We used the World Health
Organization STEPwise approach to risk factor surveillance for data collection. Age-adjusted
change in risk factors for NCDs was assessed using the mixed-effects linear regression for
continuous variables and the generalized estimating equation for categorical variables. The
mean age of participants at baseline was 41.6 years, and 53.9% were women. The mean follow-up
period was 7.1 years. There were significant increases in weight (mean change +5.0
kg, 95% confidence interval [CI] 4.2 to 5.8), body mass index (mean change +1.8 kg/m2
,
95% CI 1.5 to 2.1), waist circumference (mean change +3.9 cm, 95% CI 3.0 to 4.8), waist-toheight
ratio (mean change +0.022, 95% CI 0.016 to 0.027), current smokeless tobacco use
(men: odds ratio [OR] 1.6, 95% CI 1.1 to 2.2), alcohol use (men: OR 2.6, 95% CI 1.9 to 3.5;
women: OR 4.8, 95% CI 1.8 to 12.6), physical inactivity (OR 2.0, 95% CI 1.3 to 3.0), obesity
(OR 2.2, 95% CI 1.7 to 2.8), and central obesity (OR 1.9, 95% CI 1.5 to 2.3). Over a sevenyear
period, several NCD risk factors have increased in the study cohort. This calls for implementation
of lifestyle intervention programs in rural Kerala.
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Citation
Sathish T, Kannan S, Sarma SP, Razum O, Sauzet O, Thankappan KR. Seven-year longitudinal change in risk factors for non-communicable diseases in rural Kerala, India: The WHO STEPS approach.Plos one. 2017; 12(6).