A novel leukodepletion filter from electrospun poly(ethylene-vinyl alcohol) membranes and evaluation of its efficiency
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Date
2016-01
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International Journal of Polymeric Materials and Polymeric Biomaterials
Abstract
The authors describe the fabrication and evaluation of a novel leukodepletion filter using novel poly
(ethylene-vinyl alcohol) membranes through electrospinning. The membranes were biocompatible and
nonhemolytic. A prototype of the filter was developed by stacking the membranes in a poly(methyl
methacrylate) case. Upon whole blood filtration, the filter could achieve 100% leukodepletion while
capturing 8% red blood cells and 91% platelets. The length of filtration through the developed filter was
high when compared to that of marketed filter while overall performance of the filter was comparable to
that of the marketed filter
Description
Keywords
Biocompatibility; electrospinning; hemolysis; leukodepletion filter; poly (ethylene-vinyl alcohol) membrane
Citation
Mayuri PV, Bhatt A, Sabareeswaran A , Ramesh P. A novel leukodepletion filter from electrospun poly(ethylene-vinyl alcohol) membranes and evaluation of its efficiency. International Journal of Polymeric Materials and Polymeric Biomaterials. 2016;65(4):183-190