Incidence of type-2 diabetes among industrial Workers in Kerala, India
No Thumbnail Available
Date
2016-04
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of diabetes in developing countries
Abstract
Kerala is the most advanced Indian state in epidemiological
transition and has the highest type 2 diabetes prevalence.
However, data on incidence of diabetes in Kerala are
limited. We studied the incidence of diabetes and pre-diabetes
among industrial workers. We measured fasting plasma glucose
(FPG) among 326 workers (mean age 51 years, men
76 %) from two major industries in Kerala in the years 2009
and 2011 using standard protocol. Individuals with FPG
≥126 mg/dl or on medications for diabetes were considered
to have diabetes mellitus, FPG ≥100 mg/dl and ≤125/dl mg as
pre-diabetic, and FPG <100 mg/dl as normal. Among the 326
workers, 26.1 % (95 % CI 21.6–31.1) were diabetic, 32.8 %
(CI 28.7–37.2) were pre-diabetic, and the remaining 41.1 %
were having normal FPG at baseline. At year two, 13.3 % of
the 241 workers who were either normal or had pre-diabetes at
baseline developed diabetes providing an incidence rate of
6.65 % per year. Among the 134 workers with normal FPG
at baseline 28.4 % progressed to pre-diabetes, 5.2 % developed
diabetes, and among the 107 pre-diabetics, 23.4 % developed
diabetes at year two. The odds of progressing to
diabetes from pre-diabetes were five times higher compared
to those from normal FPG (OR 5.53; CI 2.28–13.37).
Progression to pre-diabetes and diabetes occurred at a very
fast rate in this population indicating the need for preventive
measures to slow down this fast progression
Description
Keywords
Incidence . Type 2 diabetes . Pre-diabetes . Industrial workers . Kerala . India
Citation
Thankappan KR, Mini GK, Sarma PS, Varma RP. Incidence of type-2 diabetes among industrial Workers in Kerala, India. International Journal of diabetes in developing countries. 2016.