Advanced MRI in Rosai-Dorfman disease: Correlation with histopathology
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Date
2011
Journal Title
Journal ISSN
Volume Title
Publisher
JOURNAL OF NEURORADIOLOGY
Abstract
Rosai-Dorfman disease is an idiopathic benign lymphoproliferative disorder that can, on rare occasions, cause intracranial or intraspinal lesions with non-specific features on conventional imaging. For this reason, its diagnosis is based on the classical pathological findings of histiocyte proliferation and emperipolesis. In this case report, we describe the imaging features of Rosai-Dorfman disease as visualized by newer types of MRI sequences, such as diffusion tensor imaging (DTI), susceptibility-weighted imaging (SWI) and perfusion-weighted imaging (PWI). In fact, combining the findings of conventional cross-sectional imaging with high fractional anisotropy (FA), a low apparent diffusion coefficient (ADC), mild blooming on SWI and decreased perfusion can help to make the diagnosis of Rosai-Dorfman disease. These newer tools can also be used to clarify the pathology of Rosai-Dorfman disease. (C) 2010 Elsevier Masson SAS. All rights reserved.
Description
Keywords
Neurosciences & Neurology; Radiology, Nuclear Medicine & Medical Imaging
Citation
38 ,2;113-117