A new generation of high flex life polyurethane urea for polymer heart valve-Studies on in vivo biocompatibility and biodurability

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dc.contributorThomas, Vinoy
dc.contributorJayabalan, Muthu
dc.date.accessioned2012-12-04T11:43:13Z
dc.date.available2012-12-04T11:43:13Z
dc.date.issued2009
dc.description.abstractDevelopment of new generation high flex life polyurethane urea (HFL18-PU) with appropriate elastic modulus, biocompatibility, blood compatibility, resistant to calcification, and biodurability for the long-term use as cardiac device is still a challenge. This study reports the development of a fully aliphatic, ether-free physically cross-linked and low elastic modulus (6.841 +/- 0.27 MPa) polyurethane urea having hi vivo biostability, in vivo biocompatibility and high flex-life (721 +/- 30 million cycles) that can satisfy the requirements for the fabrication of tri-leaflet heart valve. (c) 2008 Wiley Periodicals, Inc. J Biomed Mater Res 89A: 192-205, 2009
dc.identifier.citationJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. 89A; 1; 192-205en_US
dc.identifier.urihttp://dx.doi.org/10.1002/jbm.a.31937
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/25
dc.publisherJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
dc.subjectBiomaterials
dc.titleA new generation of high flex life polyurethane urea for polymer heart valve-Studies on in vivo biocompatibility and biodurability
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