Changes in polyurethane calcification due to antibiotics

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dc.contributorChandy, T
dc.contributorVasudev, SC
dc.contributorSharma, CP
dc.date.accessioned2012-12-04T11:43:37Z
dc.date.available2012-12-04T11:43:37Z
dc.date.issued1996
dc.description.abstractTo develop artificial materials for prolonged use in the vascular system, the complicated process of surface-induced calcification must be better understood. Calcification was examined on porous polyurethane incubated in metastable solutions of calcium phosphate, and the role of certain antibiotics in the medium was evaluated. It seems that certain aminoglycoside antibiotics can modify polyurethane surfaces and, subsequently, their mineralization process. In addition, these antibiotics may alter the calcium transport through polyurethanes. Therefore, it is conceivable that certain antibiotics can, in addition to producing their antibacterial effect, modulate surface calcium binding by changing the calcium mobilization and crystallization. Additional studies are needed to develop applications.
dc.identifier.citationARTIFICIAL ORGANS. 20; 7; 752-760en_US
dc.identifier.urihttp://dx.doi.org/10.1111/j.1525-1594.1996.tb04536.x
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/237
dc.publisherARTIFICIAL ORGANS
dc.subjectBiocompatibility
dc.titleChanges in polyurethane calcification due to antibiotics
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