ISOLATION OF 2 ANTIGENS FROM THE CULTURE FILTRATES OF MYCOBACTERIUM-TUBERCULOSIS AND THEIR APPLICATIONS IN THE LABORATORY DIAGNOSIS OF THE TUBERCULOUS MENINGITIS

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dc.contributorKRISHNAN, VVR
dc.contributorMATHAI, A
dc.date.accessioned2012-12-04T11:44:27Z
dc.date.available2012-12-04T11:44:27Z
dc.date.issued1991
dc.description.abstractTwo antigens were isolated from the culture filtrates of H37Ra Mycobacterium tuberculosis by immunoabsorbent affinity chromatography, M. tuberculosis antigen 5 and immunoabsorbent affinity column-purified antigen (IAP). The potential application of these two mycobacterial antigens in the laboratory diagnosis of tuberculous meningitis was evaluated by indirect enzyme-linked immunoabsorbent assay in cerebrospinal fluid specimens. IAP antigen was more sensitive than antigen 5, although antigen 5 was more specific than IAP antigen in detecting tuberculous aetiology. Technical aspects of immunoabsorbent affinity chromatography have been highlighted in this study.
dc.identifier.citationMEDICAL MICROBIOLOGY AND IMMUNOLOGY. 180; 2; 101-107en_US
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/673
dc.publisherMEDICAL MICROBIOLOGY AND IMMUNOLOGY
dc.subjectImmunology
dc.titleISOLATION OF 2 ANTIGENS FROM THE CULTURE FILTRATES OF MYCOBACTERIUM-TUBERCULOSIS AND THEIR APPLICATIONS IN THE LABORATORY DIAGNOSIS OF THE TUBERCULOUS MENINGITIS
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