ADENOSINE AND ATP - MUTUALLY EXCLUSIVE MODIFIERS OF THE KINETICS OF ADP-INDUCED AGGREGATION OF CALF-PLATELETS

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dc.contributor.authorJAMALUDDIN, M
dc.contributor.authorKRISHNAN, LK
dc.date.accessioned2017-03-10T03:25:21Z
dc.date.available2017-03-10T03:25:21Z
dc.date.issued1990
dc.description.abstractModulations of initial rate kinetics of ADP-induced aggregation of citrated calf platelet-rich plasma by adenosine and ATP were investigated employing a spectrophotometric platelet aggregation assay. The data were analysed according to the tenets of the sequential shape-change and interaction model of aggregation. Adenosine and ATP increased the slopes and intercepts of double-reciprocal plots of ADP-aggregation kinetics. Examination of their slope and intercept effects together with their effects individually and in combination, on aggregation rates, suggested that adenosine and ATP acted at multiple, nonoverlapping, sites.
dc.identifier.citation15 ,4;389-396en_US
dc.identifier.uri10.1007/BF02702680
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/9240
dc.publisherJOURNAL OF BIOSCIENCES
dc.subjectLife Sciences & Biomedicine - Other Topics
dc.titleADENOSINE AND ATP - MUTUALLY EXCLUSIVE MODIFIERS OF THE KINETICS OF ADP-INDUCED AGGREGATION OF CALF-PLATELETS
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